TEDE Communidade:http://www.bdtd.ueg.br/handle/tede/282024-03-27T12:14:11Z2024-03-27T12:14:11ZRepercussões da prática do ballet clássico no crescimento e desenvolvimento na infância e adolescênciaSantos, Rafaela Noleto doshttp://www.bdtd.ueg.br/handle/tede/14592024-03-19T16:51:44Z2019-02-28T00:00:00ZTítulo: Repercussões da prática do ballet clássico no crescimento e desenvolvimento na infância e adolescência
Autor: Santos, Rafaela Noleto dos
Primeiro orientador: Formiga, Cibelle Kayenne Martins Roberto
Abstract: The child's growth and development are subject to many influences, from heredity or environment and these aspects interact in a complex way. The practice of dance optimizes motor control, coordination of movements, balance and ability to move, developing specific dynamic posture strategies. But the changes that the practice of the Ballet provides to the body of the child and the adolescent need to be better studied. The aim of the present study was to compare the functional performance in everyday tasks and the body composition of practioners and non-practioners of classical Ballet girls and to analyze how the practice of this activity at a vocational level can influence plantar pressures and postural stability, besides to see if the vision and posture of the upper limbs can interfere with this result. A cross-sectional study was carried out with 111 girls from 10 to 15 years old, practioners (n = 56) and non- ballet practitioners (n = 55). The evaluations were: anthropometric examination, structured interview, Tanner test for sexual maturation, functional evaluation (Timed Up and Go tests, Sit and Lift and 6 Minute Walk Test) and analysis of plantar pressures and postural stability, in a baropodometry platform, in three different conditions: with eyes open and arms along the body (EOAAB), with eyes closed with arms along the body (ECAAB), and with eyes open and arms outstretched (EOAO). Data analysis was performed using group comparison, correlation and regression tests. Participants differed in mean weight, body mass index, fat percentage, anthropometric measures, sexual maturation of the breasts, socioeconomic condition and parents' schooling. In the comparison of the results of the tests, it was verified that the Ballet practitioners had better functional performance, performed lower weight discharge in the E forefoot, presented lower values of maximum pressure and plantar surface area in all evaluated conditions and had smaller displacements. It was also observed that they were more influenced by the vision and positioning of the upper limbs than the group of non-practitioners of Ballet, and that the dance time interfered in order to modify the results found. It is concluded that the vocational practice of ballet may improve physical fitness and motor development in functional activities of daily life. In addition ballet, in combination with other factors, such as weight control and selection to enter in dancer‟s companies, may contribute to delayin the development of breasts and bone maturation. The results also demonstrate that this practice influences specific characteristics of plantar pressures and visual and motor dependence in relation to the upper limbs, in order to develop specific motor strategies of corporal adaptation.
Instituição: Universidade Estadual de Goiás
Tipo do documento: Dissertação2019-02-28T00:00:00ZCaracterização, desenvolvimento tecnológico de extratos padronizados e avaliação da toxicidade de Dysphania Ambrosioides (L.) Mosyakin & Clemants (Amaranthaceae)Ferreira, Thaís Moreira Silvahttp://www.bdtd.ueg.br/handle/tede/14582024-03-19T16:51:34Z2018-09-18T00:00:00ZTítulo: Caracterização, desenvolvimento tecnológico de extratos padronizados e avaliação da toxicidade de Dysphania Ambrosioides (L.) Mosyakin & Clemants (Amaranthaceae)
Autor: Ferreira, Thaís Moreira Silva
Primeiro orientador: Paula, Joelma Abadia Marciano de
Abstract: Dysphania ambrosioides (L.) Mosyakin & Clemants (syn: Chenopodium ambrosoides L.), Amaranthaceae, is used in Brazilian folk medicine and is known as “erva-de-santa-maria” and “mastruz”. It has antiparasitic, antibacterial, anti-inflammatory, antifungal and antitumor properties. The present work aims at the characterization and technological development of the dry extract of D. ambrosioides aerial parts, standardized in flavonoids expressed as rutin, as well as the evaluation of its toxicity. The specimens were collected in the regions of Anápolis, Goiânia, Itapuranga and Pirenópolis, State of Goiás, identified and the vouchers were deposited at State University of Goiás herbarium, with number registers HUEG11387- 11392, 11873. The plant material was dried and characterized by pharmacopoeia methods. Part of the material was macerated, percolated in 70% (w/w) ethanol, in a drug/solvent ratio of 10% (w/w). The extract obtained was concentrated, characterized and added with colloidal silicon dioxide for spray-drying. The plant material was also submitted to ultrasound-assisted extraction (UAE), for which analytical methods for identification and quantification of rutin by high performance liquid chromatography (HPLC) and of total flavonoids, expressed as rutin, by spectrophotometric method were developed and validated. The processes of UAE and of dry extract standardization in flavonoids, as rutin equivalents, were optimized using a Box Behnken (33) design and the Response Surface Methodology (RSM). The standardized and characterized dry extract was subjected to in vitro and in vivo pre-clinical toxicological tests performed, respectively, in Artemia salina at concentrations of 62.5 to 1000 μg/mL, and in Wistar rats, approved by ethics commission, at dosages of 300 and 2000 mg/kg. The pharmacopoeia tests demonstrated relevant parameters in the vegetal identification of the species and quality control of the vegetal raw material. For the crude extract of aerial parts of D. ambrosioides, the high performance liquid chromatography analytical method for identification and assay of rutin was partially validated for the selectivity and linearity parameters. The spectrophotometric analytical method met the criteria of selectivity, linearity, precision, accuracy and robustness, being a fast, inexpensive and easy method to perform the dosage of flavonoids expressed as rutin. In the UAE the best conditions for the analyzed variables were: extraction time of 60 minutes, temperature of 57ºC and ethanol content of 57% (w/w). In order to obtain the standardized dry extract, the best conditions achieved in this study were: 50% (w/w) adjuvant concentration, inlet temperature of 148°C, feed flow of 0.5 L/h. For toxicological tests, the standardized dry extract was considered nontoxic in the test of Artemia salina and classified as low toxicity in the acute oral toxicity protocol in rodents, with LD50 between 2000 and 5000 mg/kg. The results obtained contribute to the development of high quality and low toxicity raw materials from D. ambrosioides aerial parts. However, chronic, sub chronic and maternal-fetal toxicity studies should be conducted.
Instituição: Universidade Estadual de Goiás
Tipo do documento: Dissertação2018-09-18T00:00:00ZA relação entre os níveis de vitamina D, força muscular e as lesões musculoesqueléticas em bailarinosAraújo, Iris Iasmine de Rezendehttp://www.bdtd.ueg.br/handle/tede/14572024-03-19T16:51:24Z2018-06-19T00:00:00ZTítulo: A relação entre os níveis de vitamina D, força muscular e as lesões musculoesqueléticas em bailarinos
Autor: Araújo, Iris Iasmine de Rezende
Primeiro orientador: Formiga, Cibelle Kayenne Martins Roberto
Abstract: Vitamin D in the body has several effects on body systems and can interfere with muscle activity. The objective of the present study was to identify vitamin D3 levels and to verify the impact of these levels on thigh muscle strength parameters and functional performance of classical ballet practitioners; characterize the health and socioeconomic conditions, life habits, sexual maturation and level of physical activity in dancers. The study had a prospective analytical cross-sectional design. The study sample consisted of 49 male and female dancers, enrolled in the Center for Professional Education in Arts Basileu França (CEPABF), in the city of Goiânia (GO). The concentration of Vitamin D was analyzed through Enzyme-linked Immunosorbent Assay (ELISA); the evaluation of muscle strength through the Muscle Strength Dynamometer of the knee joint and functional performance was evaluated through the Sit and Lift Test (SLT). For the better characterization of the sample we also used: annamese script; history of injuries, classification of the economic condition of the family of the participants through the ABEP Questionnaire 2015 (Brazilian Association of Research Companies), evaluation of the level of satisfaction with body image, evaluation of sexual maturation and type of foot dominance. It was observed that female prevailed in the sample, classified as eutrophic for BMI. 43% of the sample presented Hopovitaminosis D at the blood test. It was verified that 12 (24.49%) of the dancers presented a pubertal delay for the classification of the breasts or genitalia, when female or male, respectively, and 10 (20.41%) of the dancers presented a pubertal delay for the classification of pubic hair. As for body image distortion 23 (46.9%) had normal levels, 15 (30.6%) had mild distortion, 6 (12.2%) had moderate distortion and 5 (10.2%) had severe distortion. Concerning body image, 38 (77.6%) presented no concerns, 6 (12.2%) had mild concerns, 2 (4.1%) had moderate concerns and 3 (6.1%) had no concerns. serious concern. It was found that the mean score for the sit-up test was greater than 4.5. By Waterloo's inventory the predominant podal dominance was the right one in 34 (81%) of the dancers. The type of injury that most affected the dancers was the sprain (34.7%). The results revealed that there was a statistically significant difference between the percentage of thigh fatigue and vitamin D levels, in which dancers with normal vitamin levels had greater resistance to muscular fatigue. For the other force parameters analyzed no differences were found. The results obtained indicate that individuals with inadequate levels of this vitamin have less muscular resistance to fatigue and are therefore more susceptible to musculoskeletal injuries.
Instituição: Universidade Estadual de Goiás
Tipo do documento: Dissertação2018-06-19T00:00:00ZComplexidades clínico-laboratoriais e a perspectiva da medicina de precisão como inovação terapêutica na fibrose císticaSantos, Yasmim Queirozhttp://www.bdtd.ueg.br/handle/tede/14552024-03-19T16:51:04Z2019-02-28T00:00:00ZTítulo: Complexidades clínico-laboratoriais e a perspectiva da medicina de precisão como inovação terapêutica na fibrose cística
Autor: Santos, Yasmim Queiroz
Primeiro orientador: Ayres, Flávio Monteiro
Abstract: Cystic fibrosis is a genetic disease resulted by the CFTR complete or partially inactivation, usually due to mutations in the cftr gene. The incidence of the cftr gene mutations ranges according to ethnic groups and geographic location. The CF phenotype is partially defined by patient's genotype. Early diagnosis and genetic study are associated with many benefits in the patient’s clinical and prognostic aspects. The initial aim of this study was to analyze the clinical-laboratory complexities of CF patients attended in Goiânia. For this purpose, initially, 66 CF patients were analyzed based on the most frequent mutation F508del. After that, 51 patients were re-analyzed according to their respective mutation classes and absence of cftr mutation. We also analyzed quality of life in 24 CF patients and 12 parents and / or caregivers with the application of Cystic Fibrosis Questionnaire-Revised (CFQ-R). Another aim was to identify, based on the literature, innovations in treatment strategies targeted to our CF patients. Thus, the mutations found in patients treated in Goiânia were analyzed from the perspective of precision medicine. Our data show a review of literature with potential mutation specific drugs which target our patient’s genotype. We also investigated aerobic physical exercise and strength as a form of treatment for CF patients by a systematic literature review. Our results demonstrated that CF patients homozygous and heterozygotes F508del had a difference in the chloride values in the sweat test, and early diagnosis was associated with better clinical status. The CF patients analyzed with class IV / V mutations had a later diagnosis compared to patients with class I / II mutations. While wild type cftr patients had a lower chloride value in the sweat test compared to patients with class I / II mutations, and a better clinical picture compared to patients with mutations in the cftr gene. Approximately 22.2% of the CF patients attended in Goiânia that we analyzed are eligible for precision medicine treatments. According to the literature, aerobic and strength exercises have been shown to be beneficial for CF patients, provided that the type of exercise is prescribed in a personalized manner, regarding the modality and needs of the patient.
Instituição: Universidade Estadual de Goiás
Tipo do documento: Dissertação2019-02-28T00:00:00Z